Shoulder

Glenohumeral Osteoarthritis

Glenohumeral osteoarthritis is progressive wearing of the cartilage that lines the ball-and-socket shoulder joint. While less common than hip or knee arthritis, it causes significant pain and stiffness that can profoundly limit daily function. At Maryland Orthopedic Specialists, we guide patients through the full treatment spectrum — from physical therapy and injections to state-of-the-art shoulder replacement — to help restore comfortable, functional movement at every stage of the disease.

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What is glenohumeral osteoarthritis?

Glenohumeral (GH) osteoarthritis (OA) involves the degeneration of articular cartilage on the humeral head and/or glenoid surface, accompanied by subchondral sclerosis, osteophyte formation, and eventual loss of joint space. It is the third most common large-joint arthritis after the knee and hip.

Glenohumeral (GH) osteoarthritis (OA) involves the degeneration of articular cartilage on the humeral head and/or glenoid surface, accompanied by subchondral sclerosis, osteophyte formation, and eventual loss of joint space. It is the third most common large-joint arthritis after the knee and hip.

Primary vs. Secondary Glenohumeral OA

Primary (idiopathic) OA occurs without a clear underlying cause and is typically a disease of aging.

Secondary GH OA develops as a consequence of:

  • Post-instability arthropathy: Repetitive anterior instability events cause cartilage damage from recurrent subluxation/dislocation
  • Post-fracture: Prior Severe trauma to the proximal humerus can lead to secondary Glenohumeral Osteoarthritis. Fracture in the glenoid can also cause arthritis.
  • Avascular necrosis, septic arthritis, or crystal deposition diseases

Posterior Glenoid Erosion and Walch Classification

A characteristic pattern of posterior glenoid erosion distinguishes GH OA from other shoulder conditions. The Walch classification describes glenoid morphology on axial CT imaging and guides implant selection:

  • Type A: Centered humeral head; A1 (minor central erosion) and A2 (major central erosion)
  • Type B: Posterior subluxation of the humeral head with posterior erosion; B1 (joint space narrowing), B2 (biconcave glenoid with posterior erosion), B3 (monoconvex posterior erosion)
  • Type C: Glenoid retroversion ≥ 25°, regardless of erosion
  • Type D: Glenoid anteversion or anterior humeral subluxation

Walch B2 and B3 glenoids pose the greatest reconstructive challenge and influence glenoid component choice in shoulder arthroplasty.

Treatment options

Treatment follows a stepwise ladder based on disease severity and patient functional demands.

Physical Therapy and Activity Modification

Early GH OA responds to a program focused on range-of-motion preservation, rotator cuff strengthening, and scapular stabilization. Activity modification to reduce repetitive overhead loading helps slow symptom progression.

Oral Anti-Inflammatories and Analgesics

NSAIDs reduce inflammatory pain and improve function in mild-to-moderate OA. Selective COX-2 inhibitors are appropriate for patients with GI risk factors.

Glenohumeral Injections

- Corticosteroid injections: Effective for moderate pain relief, particularly in inflammatory phases; benefits typically last weeks to a few months. Should be used judiciously due to negative effects on the rotator cuff from corticosteroids. - Platelet rich plasma (PRP): effective for reducing symptoms from Osteoarthritis

Frequently Asked Questions

What is the difference between TSA and RSA?
Anatomic TSA mimics normal shoulder anatomy and is preferred when the rotator cuff is intact. Reverse TSA changes the biomechanics to compensate for a torn or dysfunctional rotator cuff. Our surgeons select the appropriate implant based on your specific anatomy, cuff status, and bone quality.
How long do shoulder replacements last?
Modern shoulder arthroplasty implants last 10–20 years or more in most patients. Glenoid component loosening is the most common long-term complication of anatomic TSA.
Can I delay surgery?
Yes. Surgery is elective and reserved for patients with pain and functional limitation that significantly impairs quality of life despite conservative care. We will work with you on non-surgical options as long as they remain effective.
What is the recovery timeline after shoulder replacement surgery?
After shoulder replacement, the arm is placed in a sling for four to six weeks to protect the repaired muscles and allow soft-tissue healing. Passive range-of-motion exercises begin within the first few days, and active use of the arm progressively increases over three to four months. Most patients achieve significant pain relief within the first few weeks and reach maximum functional improvement at six to twelve months. Return to light work or recreational activities typically occurs at three to four months, while overhead lifting and contact sports restrictions depend on the type of replacement performed.
What are the long-term outcomes after shoulder replacement for glenohumeral osteoarthritis?
Shoulder replacement for glenohumeral osteoarthritis has excellent long-term outcomes, with modern implants lasting 15 to 20 years in the majority of patients. Patient satisfaction rates exceed 90 percent, with dramatic improvements in pain, sleep, and shoulder function. The most common long-term concern with anatomic total shoulder replacement (TSA) is loosening of the glenoid (socket) component, which may require revision surgery after 15 or more years. At MOS we use careful pre-operative planning and implant selection to maximize implant longevity.

Meet the specialists

Christopher S. Raffo, MD

Christopher S. Raffo, MD

Orthopedic Surgery · Sports Medicine

Meet Dr. Raffo
John J. Christoforetti, MD

John J. Christoforetti, MD

Orthopedic Surgery · Sports Medicine · Hip Preservation Surgery

Meet Dr. Christoforetti
James S. Gardiner, MD

James S. Gardiner, MD

Orthopedic Surgery · Sports Medicine

Meet Dr. Gardiner

Related conditions

Medically reviewed by Christopher S. Raffo, MD
Last reviewed June 12, 2026

References

  1. Walch G, Moraga C, Young A, Castellanos-Rosas J. Results of anatomic non-constrained prosthesis in primary osteoarthritis with biconcave glenoid. J Shoulder Elbow Surg. 2012;21(11):1526–1533. doi: 10.1016/j.jse.2011.10.017.
  2. Bohsali KI, Wirth MA, Rockwood CA Jr. Complications of total shoulder arthroplasty. J Bone Joint Surg Am. 2006;88(10):2279–2292. doi: 10.2106/JBJS.F.00125.
  3. Grammont PM, Baulot E. Delta shoulder prosthesis for rotator cuff rupture. Orthopedics. 1993;16(1):65–68. PMID: 8421661.
  4. Savin DD, Zamfir P, Kuchar D, et al. Outcomes of reverse versus anatomic total shoulder arthroplasty for glenohumeral osteoarthritis with an intact rotator cuff: a systematic review. J Am Acad Orthop Surg. 2023;31(8):e365–e376. doi: 10.5435/JAAOS-D-22-00523.
  5. Throckmorton TW, Zarkadas PC, Sperling JW, Cofield RH. Radiographic stability of ingrowth humeral stems in total shoulder arthroplasty. Clin Orthop Relat Res. 2010;468(8):2122–2128. doi: 10.1007/s11999-009-1143-8.
  6. American Academy of Orthopaedic Surgeons. Shoulder Joint Replacement. OrthoInfo. https://orthoinfo.aaos.org/en/treatment/shoulder-joint-replacement/