Glenohumeral Osteoarthritis
Glenohumeral osteoarthritis is progressive wearing of the cartilage that lines the ball-and-socket shoulder joint. While less common than hip or knee arthritis, it causes significant pain and stiffness that can profoundly limit daily function. At Maryland Orthopedic Specialists, we guide patients through the full treatment spectrum — from physical therapy and injections to state-of-the-art shoulder replacement — to help restore comfortable, functional movement at every stage of the disease.
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What is glenohumeral osteoarthritis?
Glenohumeral (GH) osteoarthritis (OA) involves the degeneration of articular cartilage on the humeral head and/or glenoid surface, accompanied by subchondral sclerosis, osteophyte formation, and eventual loss of joint space. It is the third most common large-joint arthritis after the knee and hip.
Glenohumeral (GH) osteoarthritis (OA) involves the degeneration of articular cartilage on the humeral head and/or glenoid surface, accompanied by subchondral sclerosis, osteophyte formation, and eventual loss of joint space. It is the third most common large-joint arthritis after the knee and hip.
Primary vs. Secondary Glenohumeral OA
Primary (idiopathic) OA occurs without a clear underlying cause and is typically a disease of aging.
Secondary GH OA develops as a consequence of:
- Post-instability arthropathy: Repetitive anterior instability events cause cartilage damage from recurrent subluxation/dislocation
- Post-fracture: Prior Severe trauma to the proximal humerus can lead to secondary Glenohumeral Osteoarthritis. Fracture in the glenoid can also cause arthritis.
- Avascular necrosis, septic arthritis, or crystal deposition diseases
Posterior Glenoid Erosion and Walch Classification
A characteristic pattern of posterior glenoid erosion distinguishes GH OA from other shoulder conditions. The Walch classification describes glenoid morphology on axial CT imaging and guides implant selection:
- Type A: Centered humeral head; A1 (minor central erosion) and A2 (major central erosion)
- Type B: Posterior subluxation of the humeral head with posterior erosion; B1 (joint space narrowing), B2 (biconcave glenoid with posterior erosion), B3 (monoconvex posterior erosion)
- Type C: Glenoid retroversion ≥ 25°, regardless of erosion
- Type D: Glenoid anteversion or anterior humeral subluxation
Walch B2 and B3 glenoids pose the greatest reconstructive challenge and influence glenoid component choice in shoulder arthroplasty.
Treatment options
Treatment follows a stepwise ladder based on disease severity and patient functional demands.
Physical Therapy and Activity Modification
Early GH OA responds to a program focused on range-of-motion preservation, rotator cuff strengthening, and scapular stabilization. Activity modification to reduce repetitive overhead loading helps slow symptom progression.
Oral Anti-Inflammatories and Analgesics
NSAIDs reduce inflammatory pain and improve function in mild-to-moderate OA. Selective COX-2 inhibitors are appropriate for patients with GI risk factors.
Glenohumeral Injections
- Corticosteroid injections: Effective for moderate pain relief, particularly in inflammatory phases; benefits typically last weeks to a few months. Should be used judiciously due to negative effects on the rotator cuff from corticosteroids. - Platelet rich plasma (PRP): effective for reducing symptoms from Osteoarthritis
Total Shoulder Arthroplasty (Anatomic)
Conventional anatomic shoulder replacement resurfacing the humeral head and glenoid with matched components to restore normal ball-and-socket anatomy for patients with glenohumeral arthritis and a functioning rotator cuff.
Click for more Surgical ProcedureReverse Shoulder Arthroplasty
Shoulder replacement with reversed ball-and-socket geometry that allows the deltoid to power shoulder elevation when the rotator cuff is absent or irreparable. Performed for rotator cuff arthropathy, massive irreparable cuff tears, or failed prior replacement.
Click for moreFrequently Asked Questions
What is the difference between TSA and RSA?
How long do shoulder replacements last?
Can I delay surgery?
What is the recovery timeline after shoulder replacement surgery?
What are the long-term outcomes after shoulder replacement for glenohumeral osteoarthritis?
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John J. Christoforetti, MD
Orthopedic Surgery · Sports Medicine · Hip Preservation Surgery
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References
- Walch G, Moraga C, Young A, Castellanos-Rosas J. Results of anatomic non-constrained prosthesis in primary osteoarthritis with biconcave glenoid. J Shoulder Elbow Surg. 2012;21(11):1526–1533. doi: 10.1016/j.jse.2011.10.017.
- Bohsali KI, Wirth MA, Rockwood CA Jr. Complications of total shoulder arthroplasty. J Bone Joint Surg Am. 2006;88(10):2279–2292. doi: 10.2106/JBJS.F.00125.
- Grammont PM, Baulot E. Delta shoulder prosthesis for rotator cuff rupture. Orthopedics. 1993;16(1):65–68. PMID: 8421661.
- Savin DD, Zamfir P, Kuchar D, et al. Outcomes of reverse versus anatomic total shoulder arthroplasty for glenohumeral osteoarthritis with an intact rotator cuff: a systematic review. J Am Acad Orthop Surg. 2023;31(8):e365–e376. doi: 10.5435/JAAOS-D-22-00523.
- Throckmorton TW, Zarkadas PC, Sperling JW, Cofield RH. Radiographic stability of ingrowth humeral stems in total shoulder arthroplasty. Clin Orthop Relat Res. 2010;468(8):2122–2128. doi: 10.1007/s11999-009-1143-8.
- American Academy of Orthopaedic Surgeons. Shoulder Joint Replacement. OrthoInfo. https://orthoinfo.aaos.org/en/treatment/shoulder-joint-replacement/
